Metabolic disorders, such as type 2 diabetes and atherosclerosis form a cluster of different conditions caused and mediated by complex multi-molecular interactions. The presence of metabolic syndrome (MetS) is reported to predispose an individual to drug-induced liver injury (DILI), from drugs such as acetaminophen, halothane, statin. However, the molecular mechanisms PDF
Mid-infrared (MIR) spectroscopy is a widely used tool for chemical group identification and molecular structure analysis in chemical, pharmacy, agricultural and food related-samples. However, the diffraction limit prevents the commonly used MIR spectroscopy from mapping on nano-scale particle studies. In this paper, we introduce an imaging of milk PDF
Healthy diets have been encouraged to reverse non alcoholic fatty liver disease (NAFLD) and accelerate hepatic drug metabolism in diabetes. The amount, nature of fat consumed and time of day of fat consumption has become important [1] with relevance to hepatic drug metabolism [2] and the brain regulation of drug transport that may interfere with brain amyloid beta metabolism relevant to Alzheimer's disease and neurodegenerative disease [3]. The understanding the molecular PDF
Extrapyramidal symptoms (EPS) are undesired side-effects of antipsychotic treatments which include tremors, akathisia and Parkinsonism. The new generation of antipsychotics are expected to induce less EPS, however, these EPS still occurred in patients. The aim of this study was to optimize and implement a novel and robust protocol to evaluate the apparition of EPS and rank the intensity PDF
A case demonstrating the successful use of the benzodiazepine Diazepam to treat chronic vestibular neuronitis with severe vertigo is presented. The implications of the novel use of this psychiatric drug and a discussion on the probable pharmaco-kynetics involved follow. PDF