Volume 4 Issue 2

Review

PD1 – PDL1 Blockade Immunotherapy Applied as a Lung Cancer Treatment: Main Results, Proven Impact and Recent Knowledge Extensions

Nidhal B1* and Soraya F2

The ability of lung cancer to evade immunosurveillance is ensured by an "immune deficiency state" leading to a tolerance towards tumoral cell's antigens. Then, a theory that supports the anti-tumoral role of the immune system, made its strong proof, by individualization PDF

Research

Reactive Changes in Bone Marrow Biopsies: A Clinicopathological Study

El-Sherbiny S1 , El-Hawary AK1 , Eladl E1 and Zalata K1

Many diagnostic challenges arise due to insufficient experience with reactive bone marrow changes which can be sometimes confused with neoplastic disorders. PDF

Case Report

An Unusual Manifestation of a Hypothalamic Secondary Malignant Damage

Belloumi N1*, Bachouch I1 , Chermiti BAF1 and Fenniche S2

Sleep-wake disturbances are common. Description and classification of sleep disorders helped researchers to define precisely roles and interactions between different nervous structures. PDF

Review

On the Efficacy of High-dose Ascorbic Acid as Anticancer Treatment: A Literature Survey

Victor C1 andFlorentin S2

Vitamin C (ascorbic acid, ascorbate) has a controversial history in cancer treatment. Emerging evidence indicates that ascorbate in cancer treatment deserves re-examination. As research results concerning ascorbate pharmacokinetics and its mechanisms PDF

Research

The World Within Us (Or A Sketch of Consciousness Space Beyond Freudian Mental Model and Implications to Socio-Economics Modeling and Integrative Cancer Therapy)

Victor Christianto1* and Florentin Smarandache2

In this paper, we give an outline of an ongoing study to go beyond Freudian mental archetypal model. First, we discuss the essence of numerous problems that we suffer in our sophisticated and modernized society. Then we discuss possibility to reintroduce spirit into human consciousness. While we are aware that much PDF