Elevated levels of various cathepsins in cancer and inflammation necessitate exploring their potential inhibitors. Cathepsin L has been a potential drug target in these diseased conditions. In search for novel chemotherapeutic agents with better PDF
Pharyngocutaneous fistula (PCF) is the most feared complication postlaryngectomy with a reported incidence varying from 3% to 65%. Some of the factors such as prior radiotherapy, poor nutritional status, and preoperative tracheostomy significantly increase the risk of developing a PCF. PDF
Although Wilms tumor is the most common renal neoplasm in the pediatric population, other rare childhood renal neoplasms should be considered in a pediatric patient presenting with an abdominal mass. CCSK represents one of the most common tumors with "unfavorable histology" listed by the National PDF
Renal Cell Carcinoma (RCC) are rare in children, constituting less than 0.3% of all tumors and 1.8 – 6.3% of renal neoplasms in children and adolescents younger than 15 years. Xp11.2 RCC is estimated to represent one-third of pediatric RCC. RCC associated with Xp11.2 translocation has recently been discovered PDF
The current study was aimed to analyze the tumor tissue of cholangiocarcinoma from patient to identify the biomarkers at the protein level and mRNA level in cancer tissue. The tumor sample was analyzed by gene expression microarray analysis, DNA sequencing and immunohistochemistry. Gene expression analysis PDF