Volume 1 Issue 1

Review Article

High Sensitivity Detection of Tumor Gene Mutations

Powell Michael J* , Madhuri Ganta, Elena Peletskaya, Larry Pastor, Melanie Raymundo, George Wu, Jenny Wang and Aiguo Zhang.

It is widely accepted that cancer develops as a results of mutations in cell growth pathway related genes particularly those mutations that occur in growth factor receptor pathways such as the cell surface Epidermal Growth Factor PDF

Research Article

Stat3 as Potential Biomarker in Chronic Myeloid Leukemia Patients

Nahla Hamed1*, Nabil El Halawani1 , Gihan Sharara2 and Asmaa Mahmoud1

The search for non-invasive tools for cancer diagnosis and management is extremely important. STAT3 shows potential as a biomarker since it is present in the serum of healthy individuals. This study aimed at assessing the relationship PDF

Research Article

Evidence for Biphasic Effects and Differential Expression of Melatonin (MLT) Receptors in Oral Squamous Cell Carcinomas.

Farnoush M1 , Swint D1 , Kingsley K1

Previous work from this group has demonstrated that melatonin (MLT) is capable of significantly altering the growth and viability of oral cancer cell lines. The objective of this study was to explore the receptors that may modulate MLT effects in oral cancers. PDF

Case report

Alveolar echinococcus: A rare case with atypical localization

Metin MR1 , Aydin H2 , Ates OF1* , Cetin H1 and Karaoglanoglu M1

Alveolar echinococcus is a chronic parasitic infection, especially hepatobiliary system is involved, portal and biliary tract invasions are frequent, they have indistinct borders can behave just like malignant masses, may invade adjacent organs PDF

Short communication

Dietary curcumin modulates phenobarbital- and acetone-induced CYP450 2B1 and 2E1 isozymes in mice

Garg R*1, Dolas S2 and Maru GB2

Curcumin pretreatment has been shown to inhibit benzo(a)pyrene-induced cytochrome P450 1A1/1A2 isozymes in liver and lungs of mice, via its modulatory effect on their transcriptional regulator, aryl hydrocarbon receptor. However, its effects on the activities PDF