Volume 4 Issue 1

Case Report

Basal Ganglia Germinoma Associated with Down Syndrome in a Female Patient

Akira Tempaku*

Down syndrome is rarely associated with solid tumors in the central nervous system. I report on a female patient diagnosed with basal ganglia germinoma. PDF

Mini Review

Diabetes and Alzheimer's Disease

Shimon Shatzmiller1*, Galina M Zats1 , Inbal Lapidot1 and Ludmila Buzhansky1

The underlying causes of diabetes-induced CNS complications are multifactorial and are relatively little understood although it is now evident that blood-brain barrier (BBB) damage plays a significant role in diabetesdependent CNS disorders. Changes in plasma glucose levels (hyper- or hypoglycemia) have been associated with altered BBB transport PDF

Case Report

Hereditary spastic paraparesis: A novel phenotype

Fotiou Dimitrios F1 , Tzikas Euripides E1*, Papalamprou Artemis L1 , Kiltsopoulou Despina D1 , Dilo Dea B1 and Tegos Thomas J1

Although hereditary spastic paraparesis (HSP) is usually restricted to motor disturbances, chief among them being the progressive lower extremity spasticity, it may also present as complicated, with dementia being the most frequent complication. Out of 50 mutations related to HSP, only 7 of them concern autosomal dominant PDF

Letter to Editor

Are exogenous sRNAs in the Environment Absorbed Via Inhalation? If so, What Effects Might it Have on Brain Health?

Celia M Ross*

The role that small RNAs (sRNAs) play in health and disease has attracted considerable interest [1,2,3,4,5]. An area of recent speculation is the question as to whether dietary sRNAs are absorbed from the digestive tract and whether this is a form of inter-species / inter-kingdom epigenetic communication [6,7,8,9,10,11]. This possibility PDF

Mini Review

A garden and a library: Ancient wisdom for wellness

Celia M Ross*

Let us first consider gardens from the aspect of nature therapy. Natural botanical environments may help to support cognitive capabilities, mood, and well-being [2,3,4,5,6,7,8,9]. Botanical gardens and natural surroundings provide a multi-sensorial experience which can translate into feelings of peace, tranquility, gratitude, spirituality, PDF