New Neurological Disorders in a New Patient. Long Term VEGFR Inhibitors Effects

Di Capua B1 and Colloca G1*

Currently, several cancer therapies are based on neutralizing anti-VEGF antibodies and small-molecular-weight tyrosine-kinase inhibitors that target the VEGFRs. These new strategies for cancer treatment show the clinical relevance of inhibiting VEGF signal-transduction pathways that are exaggerated in pathological angiogenesis. PDF