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Interpersonal communication and interaction studies among healthcare experts and patients have been focused on for last three decades. Besides verbal and nonverbal communication, the time used with the patient or the communication ...
Cabozantinib, a potent pan-tyrosine kinase inhibitor, has been reported to provide enhanced antitumor efficacy by simultaneously inhibiting both MET and VEGF pathways, which are critical to tumor angio-genesis, survival and migration. Its very poor water solubility prevents its administration by the intra-venous route, which may be important in patients unable to take the drug ...
Hyaluronic acid drug conjugates can target anti-cancer drugs directly to tumor tissue for loco-regional treatment with enhanced bioavailability, local efficacy and reduced toxicity. In this study, the distribution and pharmacokinetics of hyaluronic acid carrier and a conjugated cisplatin anti-cancer drug were tracked by lanthanum (III) [La(III)] affinity tagging of the nanocarrier. The strong binding affinity of La(III) to HA enabled the simple ...
Benjamin Ehlers: Mr. Ehlers conceptualized the review, carried out the systematic review as well as analyses, drafted and revised the manuscript, and approved the final manuscript as submitted. ...
Starting from 2,3-diaminopyridine, several novel 2-amino [2,3:4,5] imidazo [1,2-a] [1,3,5] triazines (2-6), 2- (1H-imidazo [4,5-b] pyridine-2-yl) imino) -2,3-dihydro-1H-imidazoles (7-11), pyrido [2,3,4,5] imidazo [1,2-a] pyrimidones (13-16), 9H [1,2,4] triazolo [4,3:1,2] imidazo [4,5-b] pyridines (20-21) and 1-(1H-imidazo [4,5-b] pyridine-2-yl) -3-methyl-1H-pyrazol-5-ol ...
In spite of the breakthrough innovation in combinatorial chemistry and molecular modelling, natural products, especially medicinal plants remain one of the important sources from which pharmacologically active compounds are isolated, tested and evaluated in the discovery of new drugs, new leads and chemical entities in pharmaceutical development [1-3]. In fact, many ...
Green tea dietary supplements are sold all over the world, and consumers are buying record amounts of green tea products every year. However, the qualities of the products are poorly controlled, which may not only varies the benefit but also hurt the costumer. The purpose of this paper is to compare the contents of the major components in different Green tea supplements. ...
General Administration of Pharmaceutical Care of Ministry of Health (GAPD-MOH) is founded in December 13, 2001 by decision of Minster of Health number 2286/1/29, and passed through four major phases. Initial Phase from 2000-2001 it is boring period, Construction Phase from 2001-2007 it is building of basic pharmacy administration and pharmacy practice, Development Phase from 2007-2012 stating of new strategic ...
An 83-year-old female patient recovered from her primary Clostridium difficile-associated colitis upon antibiotic treatment and the suspension of her regular proton pump inhibitor (PPI) therapy, and had a recurrence of the infection once PPI was restarted. After the treatment of the recurrent episode, the PPI was replaced with a histamine H2 receptor blocker, and she ...
Medical note: "NOT ... any pathology is structural. Dysfunctional cases were entering the EEG. Before starting a premise we specialize in clinical neurophysiology with an experience in the last 14 years of about 12,500 ELECTROENCEFALOGRAMAS- about EEG. And so we can say positively, which is set forth below is very ...
Ficus religiosa Linn (Moraceae) is being used in traditional medicine to improve immunity hence, petroleum ether and 70% ethanol extracts (50 and 100 mg/kg, i.p.) of F. religiosa bark were screened for immunomodulatory activity by delayed type hypersensitivity (DTH), neutrophil adhesion test and cyclophosphamide-induced neutropenia in Swiss albino mice. 70% ethanol extract ...
Tamarindus indica L. is widely used as a traditional medicine for the management of diabetes mellitus beside its antihepatotoxic and anti-inflammatory activity. However, the influence of Tamarind seed on hyperglycemia and gastrointestinal dysfunctions of diabetes has not been explored so far at molecular level. The effect of 4 weeks oral treatment (120 and 240 mg/kg) of HPLC standardized Tamarind Seed aqueous extract (TSE) was ...
Iron is essential for the synthesis of hemoglobin in erythrocytes and its deficiency can causes Anemia. An estimated 1.62 billion people are suffering from Anemia worldwide with its highest prevalence in developing countries specially India. Therefore, Government of India has started a strategic nutritional and weekly iron folic acid supplementation (WIFS) program to reduce ...
Visceral pain is one of the most common type of pain in mammals, however its mechanisms of action has not clearly been understood. In common sense, prostaglandins are released depending on tissue damage to reduce the threshold of pain receptors. Thus, pharmacological inhibition of c-Raf kinase signaling ...
Drug abuse is a serious challenge in US. According to the report of the Drug Abuse Warning Network, more than 50% of the patients involved the abuse of control pharmaceuticals such as taking more than the prescribed dose of a prescription [1]. A more serious concern is that the control pharmaceuticals was taken by healthy individuals. This challenge is more specific in pain management with opioids such as morphine, oxycodone, oxymorphone, hydrocodone, hydromorphone, dihydrocodeine, methadone, meperidine, fentanyl, and buprenorphine. ...
Dr. Joseph Smith has after many years of research submitting a new development after being picked in April 17-20, 2010 by the SAWC for an Oral Award on my first patent, developed a patented engineered design in addition to (US PAT. # 6776769 BS 2 an application of a cap (US201201363A1), in Advanced Wound Care, Pharma, Biologics that offers better protection for people ...
