Voluntary control of the passage of feces and/or flatus is gained after toilet training in early childhood. Normally the anal canal is kept empty and closed all the time, full rectum induces sensations of desire to evacuate. According to social circumstances available the person can evacuate or postpone, waiting for favorable ...
In this paper, we give an outline of an ongoing study to go beyond Freudian mental archetypal model. First, we discuss the essence of numerous problems that we suffer in our sophisticated and modernized society. Then we discuss possibility to reintroduce spirit into human consciousness. While we are aware ...
The conventional treatment of OSCC comprised of wide local excision of the primary lesion with excision of normal tissue at margins in order to be at safe distance from tumor, with or without post-operative Radiotherapy or Chemotherapy. Tumor free margins is considered as the most important independent ...
MRD: Minimal Residual Disease; NGS: Next Generation Sequencing; MFC: Multiparameter Flow Cytometry; NGF: Next-Generation Flow Cytometry; ASO-qPCR: Allele Specific Oligonucleotide Quantitative Polymerase Chain Reaction; TTP: Time to Progression; MRI: Magnetic Resonance Imaging; PET: Positron ...
The pelvis is three dimensional structures and is the most common site of Chondrosarcoma. Chondrosarcoma is the 2nd most common malignant bone tumor. Peak age of presentation is 50 to 60 year of age but it can appear in childhood as well. Chondrosarcoma can be primary and secondary and graded ...
A new 2-(quinolin-2-yl) quinazolin-4(3H)-one (1) based copper (II) complex [Cu (1)2] (1:2) (2) has been successfully isolated. The structures of 1 and 2 were established on the basis of various spectroscopic analysis techniques, viz., ESI-Mass, IR, UV-Vis, SEMEDX and ESR spectra. The ligand (1) and its complex (2) exhibit an intercalative mode of binding with DNA molecule, ...
Today, it is known that the interaction between inflammatory and immune responses is mainly regulated by the cytokine network, which may produce both pro-inflammatory, such as IL-1 beta, IL-6, TNF-alpha, and anti-inflammatory cytokines, including IL-10 and TGF-beta, which are all characterized by an inhibitory ...
Ibrutinib is a disease-altering therapy. It has widespread and increasing use because of its better tolerability than other available therapies. Many studies showed the high efficacy of ibrutinib in CLL, however, its follow-up has remained quite short. Many questions have remained unanswered about long-term ibrutinib ...
Chemotherapy induced thrombocytopaenia is difficult to manage due to limited number of therapies available. A clinical experiment using Carica papaya leaf extract helped to overcome the low platelet count in 3 to 4 days. New agents for correcting thrombocytopaenia take 3 weeks to correct the platelet count. ...
Medicinal plants are important elements of indigenous medical system that have persisted in developing countries. Many of the botanical chemo-preventions currently used as potent anticancer agents. However, some important anticancer agents are still extracted from plants because they cannot be synthesized ...
Approximately 0.5% bone tumor occurs in clavicle. Primary chrondrosarcoma is very rare even among clavicle tumors. Secondary Chrondrosarcoma is reported with variable incidence. It is the third most common primary tumor arising from bone. Surgery is the only treatment option in Chondrosarcomas with excellent prognosis. We report a case of 14 years old male patient history ...
Osteosarcoma sternum and clavicle is rare tumor. We reported a case of 32 female presented with lump at sternum & right clavicle. X-ray chest showed osteoblastic lesion. MRI showed hyperintense lesion pushing the neck and superior mediastinum structures. Bone scan showed no distant metastasis. Wide margin resection of sternum with right mid clavicle done after median sternotomy. ...