BAOJ Cancer Research & Therapy

Bioaccent Online Publishing

Published Articles

Fecal Incontinence (FI) in Women and its Reconstructive Surgery; The Role of Childbirth Trauma (CBT) and Perineal Lacerations in its Pathogenesis

Voluntary control of the passage of feces and/or flatus is gained after toilet training in early childhood. Normally the anal canal is kept empty and closed all the time, full rectum induces sensations of desire to evacuate. According to social circumstances available the person can evacuate or postpone, waiting for favorable ...

A Sketch of Consciousness Space beyond Freudian Mental Model and Implications to Socio-Economic Modeling and Integrative Cancer Therapy

In this paper, we give an outline of an ongoing study to go beyond Freudian mental archetypal model. First, we discuss the essence of numerous problems that we suffer in our sophisticated and modernized society. Then we discuss possibility to reintroduce spirit into human consciousness. While we are aware ...

Evaluation of Safe Surgical Mucosal Margins with and without Intra-Operative Vital Staining with Toluidine Blue in Cases of Oral Squamous Cell Carcinoma – A Comparative Study

The conventional treatment of OSCC comprised of wide local excision of the primary lesion with excision of normal tissue at margins in order to be at safe distance from tumor, with or without post-operative Radiotherapy or Chemotherapy. Tumor free margins is considered as the most important independent ...

Minimal Residual Disease Assessment in Multiple Myeloma is A Major Challenge in Clinical Practice

MRD: Minimal Residual Disease; NGS: Next Generation Sequencing; MFC: Multiparameter Flow Cytometry; NGF: Next-Generation Flow Cytometry; ASO-qPCR: Allele Specific Oligonucleotide Quantitative Polymerase Chain Reaction; TTP: Time to Progression; MRI: Magnetic Resonance Imaging; PET: Positron ...

Chondrosarcoma Pelvis; A Review Article

The pelvis is three dimensional structures and is the most common site of Chondrosarcoma. Chondrosarcoma is the 2nd most common malignant bone tumor. Peak age of presentation is 50 to 60 year of age but it can appear in childhood as well. Chondrosarcoma can be primary and secondary and graded ...

New Copper (II) 2-(Quinolin-2-Yl) Quinazolin-4(3H)-One Complex and Study of its DNA Binding, Antibacterial, Docking and Cytotoxic Properties

A new 2-(quinolin-2-yl) quinazolin-4(3H)-one (1) based copper (II) complex [Cu (1)2] (1:2) (2) has been successfully isolated. The structures of 1 and 2 were established on the basis of various spectroscopic analysis techniques, viz., ESI-Mass, IR, UV-Vis, SEMEDX and ESR spectra. The ligand (1) and its complex (2) exhibit an intercalative mode of binding with DNA molecule, ...

The Balance Betwwen Inflammatory and Anti-Inflammatory Responses as the Paradigma of the Status of Health

Today, it is known that the interaction between inflammatory and immune responses is mainly regulated by the cytokine network, which may produce both pro-inflammatory, such as IL-1 beta, IL-6, TNF-alpha, and anti-inflammatory cytokines, including IL-10 and TGF-beta, which are all characterized by an inhibitory ...

What is the place of single-agent ibrutinib in the current landscape of CLL?

Ibrutinib is a disease-altering therapy. It has widespread and increasing use because of its better tolerability than other available therapies. Many studies showed the high efficacy of ibrutinib in CLL, however, its follow-up has remained quite short. Many questions have remained unanswered about long-term ibrutinib ...

Thrombopoiesis in Chemotherapy-Induced Thrombocytopaenia Using Carica Papaya Leaf Extract – An Attentive Clinical Observation

Chemotherapy induced thrombocytopaenia is difficult to manage due to limited number of therapies available. A clinical experiment using Carica papaya leaf extract helped to overcome the low platelet count in 3 to 4 days. New agents for correcting thrombocytopaenia take 3 weeks to correct the platelet count. ...

On the Efficacy of Moringa Oleifera as Anticancer Treatment: A Literature Survey

Medicinal plants are important elements of indigenous medical system that have persisted in developing countries. Many of the botanical chemo-preventions currently used as potent anticancer agents. However, some important anticancer agents are still extracted from plants because they cannot be synthesized ...

Secondary Chrondrosarcoma of Clavicle Due to Multiple Hereditary Exostosis in Adolescent

Approximately 0.5% bone tumor occurs in clavicle. Primary chrondrosarcoma is very rare even among clavicle tumors. Secondary Chrondrosarcoma is reported with variable incidence. It is the third most common primary tumor arising from bone. Surgery is the only treatment option in Chondrosarcomas with excellent prognosis. We report a case of 14 years old male patient history ...

Sternum & Clavicle Osteosarcoma: A Case Report &Literature Review

Osteosarcoma sternum and clavicle is rare tumor. We reported a case of 32 female presented with lump at sternum & right clavicle. X-ray chest showed osteoblastic lesion. MRI showed hyperintense lesion pushing the neck and superior mediastinum structures. Bone scan showed no distant metastasis. Wide margin resection of sternum with right mid clavicle done after median sternotomy. ...